Drug Discovery
10 articles
Basic science research funding is falling behind AI hype.
The foundational research that yielded life-changing GLP-1 drugs is currently under attack.
What Are Deep Sea Life Adaptations and Their Biomedical Potential?
Pharmaceuticals derived from marine organisms boast success rates two to four times higher than those from terrestrial sources.
Eli Lilly invests in AI startup Absci for new hair loss treatments
Despite 71% of adolescents with severe alopecia achieving successful hair regrowth with its existing drug, Eli Lilly is now betting on an early-stage AI startup for hair loss treatments.
AI Drug Development Surges: In Silico Trials Market Grows Dramatically
Biotech firm Insilico Medicine used artificial intelligence to discover a novel drug candidate for idiopathic pulmonary fibrosis (IPF) and advance it to Phase I clinical trials in under 30 months, acc
Alnylam partners with Inceptive Nucleics for AI-driven RNAi therapeutics
Alnylam Pharmaceuticals, a leader in RNAi therapeutics, just committed $30 million upfront and up to $2 billion to Silicon Valley biotech startup Inceptive Nucleics.
New drug Bepirovirsen functionally cures hepatitis B in some patients
In two late-stage clinical trials, GSK's experimental drug Bepirovirsen achieved a functional cure for 19% of patients with chronic hepatitis B, a disease that has long resisted effective treatment.
New Study Revisits Brain Theory and Neuroscience Concepts
Researchers recently pinpointed that the weight-loss effects of the GLP-1 drug semaglutide hinge on increased levels of a single molecule, cyclic adenosine monophosphate (cAMP), in a specific brain re
UW Medicine AI designs novel miniproteins targeting GPCRs
In one mouse study, a designed miniprotein performed comparably to a clinically used drug with fewer side effects, offering a glimpse into safer treatments for human diseases.
New Quintuple Agonist Targets GLP-1R, GIPR, PPARs in Mice
In mouse models, an experimental obesity and diabetes drug called GLP-1-GIP-Lani not only corrected obesity and diabetes but also significantly outperformed semaglutide in lowering body weight, food i
AI Powers Advances in Drug Discovery and Cancer Detection
A Mayo Clinic-developed AI model can now detect pancreatic cancer on routine CT scans up to three years before a clinical diagnosis.